ALERT

In observance of US Thanksgiving holiday, Agilent Cross Lab iLab Operations Software will be closed during US hours on Thursday November 23rd and Friday November 24th, 2017. EU and APAC support coverage will remain open during this time. We will resume US support hours on Monday November 27th, 2017. For urgent matters, please add "URGENT" to the ticket subject and these requests will be prioritized first.

Live Tumor Culture Core (LTCC) / (SCCC)

Overview of Services

The goal of the Live Tumor Culture Core (LTCC) is to provide to the research community:

  • Primary normal human cell lines
  • Primary human tumor cell lines
  • Custom media
  • Viably preserved tumor cell ready for establishing cell lines

Standard cell culture systems are only able to generate new cell lines in less than 1% of human tumors. We have developed a new technology that improves this greatly to a success rate of more than 90% over a wide range of tissues.
We anticipate sixty-one highly characterized and validated primary human and engineered cell lines to be available and will be added along with additional tissue types and cell lines as they become available.

Leadership

Scientific Director

Tan A. Ince, M.D., Ph.D.

Phone: (305) 243-1782

E-mail: Tince@med.miami.edu

 

Core Administrator

Shalini Hayes

Phone: (305) 243-4608

E-mail: LTCC@med.miami.edu

 

Media Preparation and Cell Line Expansion

Michelle Jones, B.A.

Phone: (305) 243-2932

E-mail: Mjones5@med.miami.edu

 

SunHwa Hong, Ph.D.

Phone: (305) 243-2932

E-mail: sxh739@med.miami.edu

 

Location and Hours of Operation

Hours Location

Monday - Friday

8:30 AM - 5:00 PM      

Biomedical Research Building

1501 NW 10th Avenue, Miami, FL 33136

Links and Resources

  1. University of Miami Core Website

Contacts

Name Role Phone Email Location
Shalini Hayes
Core Administrator
 
(305) 243-4608
 
LTCC@med.miami.edu
 
Biomedical Research Buildiing
 

Services

Name Description
SC1 - OCMI - E Culture Medium (Only Avaialbe for Collaborative Projects, contact LTCC for details)   
SC10 - BMI-P Culture Medium 
Use Normal human breast epithelium
Primary Reference to cite in publications Ince et al., Cancer Cell 2007
 
SC13 - FNE1 Cell Line 
Histotype Fallopian Non-Ciliated
Medium Name FOMI
Notes Immortalized with hTERT-pgp
Primary Reference to cite in publications Ince et al., PLOS ONE, 2013
Online Data GSE37648
 
SC13 - FNE2 Cell Line 
Histotype Fallopian Non-Ciliated
Medium Name FOMI
Notes Immortalized with hTERT-pgp
Primary Reference to cite in publications Ince et al., PLOS ONE, 2013
Online Data GSE37648
 
SC13 - FNLE1 Cell Line 
Histotype Fallopian Non-Ciliated
Medium Name FOMI
Notes Transformed with hTERT-gfp + LT/st
Primary Reference to cite in publications Ince et al., PLOS ONE, 2013
Online Data GSE37648
 
SC13 - FNLE2 Cell Line 
Histotype Fallopian Non-Ciliated
Medium Name FOMI
Notes Transformed with hTERT-gfp + LT/st
Primary Reference to cite in publications Ince et al., PLOS ONE, 2013
Online Data GSE37648
 
SC13 - FNLER1 Cell Line 
Histotype Fallopian Non-Ciliated
Medium Name FOMI
Notes Transformed with hTERT-gfp + LT/st + H-Ras
Primary Reference to cite in publications Ince et al., PLOS ONE, 2013
Online Data GSE37648
 
SC13 - FNLER2 Cell Line 
Histotype Fallopian Non-Ciliated
Medium Name FOMI
Notes Transformed with hTERT-gfp + LT/st + H-Ras
Primary Reference to cite in publications Ince et al., PLOS ONE, 2013
Online Data GSE37648
 
SC13 - MZE Cell Line 
Histotype Mesothelium
Medium Name DME:F12 (Non-LTCC Vendor)
Notes Transformed with hTERT-gfp + LT/st
Primary Reference to cite in publications Iwanicki et al., Cancer Discov. 2011
Publications in which the cells were used Davidowitz et al.,     J Clin Invest. 2014
 
SC13 - OCE1 Cell Line 
Histotype Ovarian Surface
Medium Name FOMI
Notes Immortalized with Htert-pgp
Primary Reference to cite in publications Ince et al., PLOS ONE, 2013
Online Data GSE37648
 
SC13 - OCE2 Cell Line 
Histotype Ovarian Surface
Medium Name FOMI
Notes Immortalized with Htert-pgp
Primary Reference to cite in publications Ince et al., PLOS ONE, 2013
Online Data GSE37648
 
SC13 - OCLE1 Cell Line 
Histotype Ovarian Surface
Medium Name FOMI
Notes Transformed with hTERT-gfp + LT/st
Primary Reference to cite in publications Ince et al., PLOS ONE, 2013
Online Data GSE37648
 
SC13 - OCLE2 Cell Line 
Histotype Ovarian Surface
Medium Name FOMI
Notes Transformed with hTERT-gfp + LT/st
Primary Reference to cite in publications Ince et al., PLOS ONE, 2013
Online Data GSE37648
 
SC13 - OCLER1 Cell Line 
Histotype Ovarian Surface
Medium Name FOMI
Notes Transformed with hTERT-gfp + LT/st + H-Ras
Primary Reference to cite in publications Ince et al., PLOS ONE, 2013
Online Data GSE37648
 
SC14 - FCI-P2p Cell Line 
Histotype Serous Primary
Medium Name OCMI-L
Notes To establish new OCI lines, contact LTCC for specialized medium.
Primary Reference to cite in publications Ince et al., Nature Communications, 2015
Publications in which the cells were used Ince et al., Clin Cancer Res., 2012
Online Data GSE40785
GSE40786
GSE40787
GSE40788
 
 
SC14 - OCI-C1p Cell Line 
Histotype Clear Cell Primary
Medium Name OCMI-L
Notes Use OCMI-L medium for established OCI lines only. 
Primary Reference to cite in publications Ince et al., Nature Communications, 2015
Publications in which the cells were used Ince et al., Clin Cancer Res., 2012
Online Data GSE40785
GSE40786
GSE40787
GSE40788
 
 
SC14 - OCI-C4p Cell Line 
Histotype Clear Cell Primary
Medium Name OCMI-L
Notes Use OCMI-L medium for established OCI lines only. 
Primary Reference to cite in publications Ince et al., Nature Communications, 2015
Publications in which the cells were used Ince et al., Clin Cancer Res., 2012
Online Data GSE40785
GSE40786
GSE40787
GSE40788
 
 
SC14 - OCI-C5x Cell Line 
Histotype Clear Cell Xenograft
Medium Name OCMI-L
Notes Use OCMI-L medium for established OCI lines only. 
Primary Reference to cite in publications Ince et al., Nature Communications, 2015
Publications in which the cells were used Ince et al., Clin Cancer Res., 2012
Online Data GSE40785
GSE40786
GSE40787
GSE40788
 
 
SC14 - OCI-CSp Cell Line 
Histotype Carcinosarcoma
Medium Name OCMI-L
Notes To establish new OCI lines, contact LTCC for specialized medium.
Primary Reference to cite in publications Ince et al., Nature Communications, 2015
Publications in which the cells were used Ince et al., Clin Cancer Res., 2012
Online Data GSE40785
GSE40786
GSE40787
GSE40788
 
 
SC14 - OCI-D1p Cell Line 
Histotype Dysgerminoma
Medium Name OCMI-L
Notes To establish new OCI lines, contact LTCC for specialized medium.
Primary Reference to cite in publications Ince et al., Nature Communications, 2015
Publications in which the cells were used Ince et al., Clin Cancer Res., 2012
Online Data GSE40785
GSE40786
GSE40787
GSE40788
 
 
SC14 - OCI-E1p Cell Line - Requires a low oxygen incubator 
Histotype Endometrioid Primary
Medium Name OCMI-Le
Notes Supplement with E2
Primary Reference to cite in publications Ince et al., Nature Communications, 2015
Publications in which the cells were used Ince et al., Clin Cancer Res., 2012
Online Data GSE40785
GSE40786
GSE40787
GSE40788
 
 
SC14 - OCI-EP1p Cell Line - Requires a low oxygen incubator 
Histotype Endometrioid Primary
Medium Name OCMI-Le
Notes Supplement with E2
Primary Reference to cite in publications Ince et al., Nature Communications, 2015
Publications in which the cells were used Ince et al., Clin Cancer Res., 2012
Online Data GSE40785
GSE40786
GSE40787
GSE40788
 
 
SC14 - OCI-M1p Cell Lines - Requires a low oxygen incubator 
Histotype Mucinous Primary
Medium Name OCMI-Le
Notes Supplement with E2
Primary Reference to cite in publications Ince et al., Nature Communications, 2015
Publications in which the cells were used Ince et al., Clin Cancer Res., 2012
Online Data GSE40785
GSE40786
GSE40787
GSE40788
 
 
SC14 - OCI-P2a Cell Line - Requires a low oxygen incubator 
Histotype Serous Ascites
Medium Name OCMI-L
Notes Use OCMI-L medium for established OCI lines only. 
Primary Reference to cite in publications Ince et al., Nature Communications, 2015
Publications in which the cells were used Ince et al., Clin Cancer Res., 2012
Online Data GSE40785
GSE40786
GSE40787
GSE40788
 
 
SC14 - OCI-P5x Cell Line 
Histotype Serous Xenograft
Medium Name OCMI-L
Notes To establish new OCI lines, contact LTCC for specialized medium.
Primary Reference to cite in publications Ince et al., Nature Communications, 2015
Publications in which the cells were used Ince et al., Clin Cancer Res., 2012
Online Data GSE40785
GSE40786
GSE40787
GSE40788
 
 
SC14 - OCI-P7a Cell Line - Requires a low oxygen incubator 
Histotype Serous Ascites
Medium Name OCMI-L
Notes To establish new OCI lines, contact LTCC for specialized medium.
Primary Reference to cite in publications Ince et al., Nature Communications, 2015
Publications in which the cells were used Ince et al., Clin Cancer Res., 2012
Online Data GSE40785
GSE40786
GSE40787
GSE40788
 
 
SC14 - OCI-P8p Cell Line - Requires a low oxygen incubator 
Histotype Serous Primary
Medium Name OCMI-L
Notes To establish new OCI lines, contact LTCC for specialized medium.
Primary Reference to cite in publications Ince et al., Nature Communications, 2015
Publications in which the cells were used Ince et al., Clin Cancer Res., 2012
Online Data GSE40785
GSE40786
GSE40787
GSE40788
 
 
SC14 - OCI-P9a1 Cell Line - Requires a low oxygen incubator 
Histotype Serous Ascites
Medium Name OCMI-L
Notes To establish new OCI lines, contact LTCC for specialized medium.
Primary Reference to cite in publications Ince et al., Nature Communications, 2015
Publications in which the cells were used Ince et al., Clin Cancer Res., 2012
Online Data GSE40785
GSE40786
GSE40787
GSE40788
 
 
SC14 - OCI-P9a2 Cell Line 
Histotype Serous Primary
Medium Name OCMI-L
Notes Allow 6-8 weeks for expansion due to slow growth
Primary Reference to cite in publications Ince et al., Nature Communications, 2015
Publications in which the cells were used Ince et al., Clin Cancer Res., 2012
Online Data GSE40785
GSE40786
GSE40787
GSE40788
 
 
SC14 - OCI-U1a Cell Line 
Histotype Mullerian Ascites
Medium Name OCMI-L
Notes To establish new OCI lines, contact LTCC for specialized medium.
Primary Reference to cite in publications Ince et al., Nature Communications, 2015
Publications in which the cells were used Ince et al., Clin Cancer Res., 2012
Online Data GSE40785
GSE40786
GSE40787
GSE40788
 
 
SC15 - BPE2 Cell Line 
Histotype Breast Luminal
Medium Name BMI-P
Notes Immortalized with hTERT-pgp
Primary Reference to cite in publications Ince et al.,   Cancer Cell, 2007
Publications in which the cells were used Godar et al., Cell, 2008
Online Data GSE6885
  GSE48444
 
SC15 - BPE3 Cell Line 
Histotype Breast Luminal
Medium Name BMI-P
Notes Immortalized with hTERT-pgp
Primary Reference to cite in publications Ince et al.,   Cancer Cell, 2007
Publications in which the cells were used Godar et al., Cell, 2008
Online Data GSE6885
  GSE48444
 
SC15 - BPE4 Cell Line 
Histotype Breast Luminal
Medium Name BMI-P
Notes Immortalized with hTERT-pgp
Primary Reference to cite in publications Ince et al.,   Cancer Cell, 2007
Publications in which the cells were used Godar et al., Cell, 2008
Online Data GSE6885
  GSE48444
 
SC15 - BPLE1 Cell Line 
Histotype Breast Luminal
Medium Name BMI-I
Notes Transformed with hTERT-gfp + LT/st
Primary Reference to cite in publications Ince et al.,   Cancer Cell, 2007
Online Data GSE6885
  GSE48444
 
SC15 - BPLE2 Cell Lines 
Histotype Breast Luminal
Medium Name BMI-I
Notes Transformed with hTERT-gfp + LT/st
Primary Reference to cite in publications Ince et al.,   Cancer Cell, 2007
Online Data GSE6885
  GSE48444
 
SC15 - BPLE3 Cell Lines 
Histotype Breast Luminal
Medium Name BMI-I
Notes Transformed with hTERT-gfp + LT/st
Primary Reference to cite in publications Ince et al.,   Cancer Cell, 2007
Online Data GSE6885
  GSE48444
 
SC15 - BPLE4 Cell Lines 
Histotype Breast Luminal
Medium Name BMI-I
Notes Transformed with hTERT-gfp + LT/st
Primary Reference to cite in publications Ince et al.,   Cancer Cell, 2007
Online Data GSE6885
  GSE48444
 
SC15 - BPLER1 Cell Line 
Histotype Breast Luminal
Medium Name BMI-T
Notes Transformed with hTERT-gfp + LT/st + H-Ras
Primary Reference to cite in publications Ince et al.,   Cancer Cell, 2007
Publications in which the cells were used Petrocca et al., Cancer Cell, 2013
  Godar et al. Cell, 2008
  McAllister et al., Cell, 2008
  Mendillo et al., Cell, 2012
Online Data GSE6885
  GSE48444
 
SC15 - BPLER2 
Histotype Breast Luminal
Medium Name BMI-T
Notes Transformed with hTERT-gfp + LT/st + H-Ras
Primary Reference to cite in publications Ince et al.,   Cancer Cell, 2007
Publications in which the cells were used Petrocca et al., Cancer Cell, 2013
  Godar et al. Cell, 2008
  McAllister et al., Cell, 2008
  Mendillo et al., Cell, 2012
Online Data GSE6885
  GSE48444
 
SC15 - BPLER3 
Histotype Breast Luminal
Medium Name BMI-T
Notes Transformed with hTERT-gfp + LT/st + H-Ras
Primary Reference to cite in publications Ince et al.,   Cancer Cell, 2007
Publications in which the cells were used Petrocca et al., Cancer Cell, 2013
  Godar et al. Cell, 2008
  McAllister et al., Cell, 2008
  Mendillo et al., Cell, 2012
Online Data GSE6885
  GSE48444
 
SC15 - BPLER4 
Histotype Breast Luminal
Medium Name BMI-T
Notes Transformed with hTERT-gfp + LT/st + H-Ras
Primary Reference to cite in publications Ince et al.,   Cancer Cell, 2007
Publications in which the cells were used Petrocca et al., Cancer Cell, 2013
  Godar et al. Cell, 2008
  McAllister et al., Cell, 2008
  Mendillo et al., Cell, 2012
Online Data GSE6885
  GSE48444
 
SC15 - HME2 Cell Line 
Histotype Breast Myoepithelial
Medium Name MEGM (Non-LTCC Vendor)
Notes Immortalized with hTERT-pgp
Primary Reference to cite in publications Ince et al.,   Cancer Cell, 2007
Publications in which the cells were used Godar et al., Cell, 2008
Online Data GSE6885
  GSE48444
 
SC15 - HME4 Cell Lines 
Histotype Breast Myoepithelial
Medium Name MEGM (Non-LTCC Vendor)
Notes Immortalized with hTERT-pgp
Primary Reference to cite in publications Ince et al.,   Cancer Cell, 2007
Publications in which the cells were used Godar et al., Cell, 2008
Online Data GSE6885
  GSE48444
 
SC15 - HMLE2 Cell Lines 
Histotype Breast Myoepithelial
Medium Name MEGM (Non-LTCC Vendor)
Notes Transformed with hTERT-gfp + LT/st
Primary Reference to cite in publications Ince et al.,   Cancer Cell, 2007
Online Data GSE6885
  GSE48444
 
SC15 - HMLE3 Cell Line 
Histotype Breast Myoepithelial
Medium Name MEGM (Non-LTCC Vendor)
Notes Transformed with hTERT-gfp + LT/st
Primary Reference to cite in publications Ince et al.,   Cancer Cell, 2007
Online Data GSE6885
  GSE48444
 
SC15 - HMLE4 Cell Line  
Histotype Breast Myoepithelial
Medium Name MEGM (Non-LTCC Vendor)
Notes Transformed with hTERT-gfp + LT/st
Primary Reference to cite in publications Ince et al.,   Cancer Cell, 2007
Online Data GSE6885
  GSE48444
 
SC15 - HMLER2 
Histotype Breast Myoepithelial
Medium Name MEGM (Non-LTCC Vendor)
Notes Transformed with hTERT-gfp + LT/st + H-Ras
Primary Reference to cite in publications Ince et al.,   Cancer Cell, 2007
Publications in which the cells were used Petrocca et al., Cancer Cell, 2013
  Godar et al. Cell, 2008
  McAllister et al., Cell, 2008
  Mendillo et al., Cell, 2012
Online Data GSE6885
  GSE48444
 
SC15 - HMLER3 
Histotype Breast Myoepithelial
Medium Name MEGM (Non-LTCC Vendor)
Notes Transformed with hTERT-gfp + LT/st + H-Ras
Primary Reference to cite in publications Ince et al.,   Cancer Cell, 2007
Publications in which the cells were used Petrocca et al., Cancer Cell, 2013
  Godar et al. Cell, 2008
  McAllister et al., Cell, 2008
  Mendillo et al., Cell, 2012
Online Data GSE6885
  GSE48444
 
SC15 - HMLER4 
Histotype Breast Myoepithelial
Medium Name MEGM (Non-LTCC Vendor)
Notes Transformed with hTERT-gfp + LT/st + H-Ras
Primary Reference to cite in publications Ince et al.,   Cancer Cell, 2007
Publications in which the cells were used Petrocca et al., Cancer Cell, 2013
  Godar et al. Cell, 2008
  McAllister et al., Cell, 2008
  Mendillo et al., Cell, 2012
Online Data GSE6885
  GSE48444
 
SC2 - OCMI-Le Culture Medium 
Use Established OCI Lines
Primary Reference to cite in publications Ince et al., Nature Communications 2015
 
SC3 - FOMI Culture Medium 
Use Normal ovary and fallopian tube epithelium
  Genetically engineered ovary and fallopian cancer cells
Primary Reference to cite in publications Ince et al., PLOS ONE, 2013
 
SC5 - TLMI Culture Medium 
Use Human T-Cell Leukemia
Primary Reference to cite in publications Ince et al., Leukemia, 2012
 
SC8 - BMI-T Culture Medium 
Use Genetically engineered breast cancer cells
Primary Reference to cite in publications Ince et al., Cancer Cell 2007
 
SC9 - BMI-I Culture Medium 
Use Normal human breast epithelium
Primary Reference to cite in publications Ince et al., Cancer Cell 2007
 

Services Available


Search available services: View: by category alphabetically
Culture Medium (7)
Primary Human Ovarian Carcinoma Cell Lines (16)
Normal Immortalized Breast Cell Lines (5)
Normal Immortalized Fallopian Tube Cell Lines (2)
Normal Immortalized Ovary Cell Lines (2)
Transformed Mezothelial Cell Lines (1)
Transformed Breast Cell Lines (7)
Transformed Fallopian Tube Cell Lines (2)
Transformed Ovary Cell Lines (2)
Tumorigenic Breast Cell Lines (7)
Tumorigenic Fallopian Tube Cell Lines (2)
Tumorigenic Ovary Cell Lines (1)